Clinical observation of levofloxacin hydrochloride ear drops combined with triamcinolone acetonide injection in the treatment of acute suppurative otitis media

Abstract

Objective To observe the clinical efficacy of levofloxacin hydrochloride ear drops combined with triamcinolone acetonide injection on acute suppurative otitis media. Methods Using random number table method, 68 patients with acute suppurative otitis media in hospital from Jan.2017 to Mar.2018 were divided into two groups, 34 cases in each group. Both groups were given oral cefuroxime axetil based therapy. The control group was treated with levofloxacin hydrochloride ear drops. The treatment group was treated with intratympanic injection of triamcinolone acetonide injection on the basis of the control group. Both groups were treated for 10 d. Results After treatment, the levels of CRP, IL-8 and TNF-α in both groups were lower than those before treatment (P 0.05). Conclusions Levofloxacin hydrochloride ear drops combined with triamcinolone acetonide injection in the treatment of acute suppurative otitis media can reduce the degree of inflammation in the body, improve the clinical symptoms, shorten the course of the disease, improve the clinical efficacy, and has good safety. Key words: Levofloxacin hydrochloride ear drops; Triamcinolone acetonide injection; Acute otitis media; Curative effect observation