Abstract

Objective To evaluate the effficacy of limbal stem cell autografting combined with mitomycin C for treatment of pterygium.Methods 52 cases were divided into 2 groups,with 26 in each group.One group received autologous limbal stem cells autografting,the other group received the same operation with mitomycin C.The cases were followed up for 6 months to 2 years.Results Corneal epithelia of limbal stem cells autografting group recovered quickly and postoperative response was slight.The recovering time of corneal epithelia was (3 + 0.5 ) d.Comesl epithelia of group with mitomycin C recovered slowly,irritating response was strong and lasted for a long time.The recovering time of cornesl epithelia was (7 ± 0.5 ) d.One case reoccurred in each group and the reoccurrance rate was 3.8%.Two cases had melt conjunctival grafts in mitomycin C group.Conclusions Two groups have low recurrence rate.We should know the indication for application of mitomycin C and pay more attention to its complications. Key words: Limbal stem cell; autografting; Mitomycin C; Pterygium

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