Abstract

The aging of Brazilian population is inevitable. Thus, this article reviews the main aspects related to the elderly population, taking into account the particularities and problems encountered in the clinical laboratory when serving this population group. We start with a brief review of the aging process physiology and then discuss the difficulties of pre-analytical (appropriateness of care), analytical (main issues for this age group sorted into body system categories) and post-analytical phases.

Highlights

  • The aging process, or senescence, used here as a synonym, is a topic that is not thoroughly understood

  • This article reviews the main aspects related to the elderly population, taking into account the particularities and problems encountered in the clinical laboratory when serving this population group

  • We start with a brief review of the aging process physiology and discuss the difficulties of pre-analytical, analytical and post-analytical phases

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Summary

Clinical laboratory findings in the elderly

Alvaro Pulchinelli Junior; Abrão José Cury Jr.; Antônio Cantero Gimenes key words Clinical laboratory Elderly Geriatrics Physiology of aging abstract. This article reviews the main aspects related to the elderly population, taking into account the particularities and problems encountered in the clinical laboratory when serving this population group. We start with a brief review of the aging process physiology and discuss the difficulties of pre-analytical (appropriateness of care), analytical (main issues for this age group sorted into body system categories) and post-analytical phases. Este artigo faz uma revisão dos principais aspectos referentes a essa população, sempre considerando as particularidades e os problemas observados no atendimento dessa faixa de população no laboratório clínico. Partimos de uma breve revisão sobre a fisiologia do envelhecimento para então percorrermos as dificuldades das fases pré-analítica (adequação do atendimento), analítica (principais problemas dessa faixa etária, divididos por sistemas orgânicos) e pós-analítica

Fisiologia do envelhecimento
Introduction
Biological aspects of aging
Evolutionary theory
Cellular senescence
Systemic theory
Cardiovascular system
Respiratory system
Nutritional and metabolic factors
Laboratory aspects
Endocrine changes
Assessment of renal function
Hematological features
Markers of inflammatory activity
Monitoring of therapeutic drugs
Findings
Conclusion
Full Text
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