Abstract

Background: Ventilator-associated pneumonia (VAP) are frequently nosocomial infections at intensive care units (ICU). VAP result in increasing ICU stay, cost and mortality rate. Microorganisms which caused VAP were variety, change of state continously with high rate antibiotic-resistance. For the high quality of treatment therapy, physians must be care about etiology, clinical and laboratory characteristics of VAP for prevention and target treatment. Objectives: To describe the clinical and laboratory characteristics of VAP and comment the result of VAP treatment. Materials and method: Cross-section study of 30 patients who were diagnosed VAP from 04/01/2017 to 04/01/2018 at Anesthesia and Critical Care Department of Hue University of Medicine and Pharmacy Hospital. Results: Mean age of patients was 72.3 ± 14.3. Early VAP was 30%, lately VAP was 70%. Fever and increase mucus sputum were main clinical characteristics of VAP. Microorganisms which caused disease were A. baumannii, S. aureus, P. aeruginosa and Enterobacter spp with high rate antibiotic resistance. Mean mechanical ventilation was 16.8 ± 9.3 days. Mean ICU treatment was 23.7 ± 11.7 days. The mortality of VAP was 46.6%. Conclusion: VAP caused increase ICU stay and mortality rate of patients. It’s essential in a bundle care for VAP prevention and early treatment based on VAP etiology. Key words: Ventilator-associated pneumonia (VAP)

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