Clinical infection characteristics and drug resistance analysis on Staphylococcus epidermidis in Shanxi Province

Abstract

Objective To analyze the clinical infection characteristics and drug resistance of Staphylococcus epidermidis isolated from infectious ocular diseases in Shanxi Province, so as to guide clinical medication. Methods One hundred and fourteen strains of Staphylococcus epidermidis isolated from specimens of patients with infectious eye diseases. The bacterial classification and antimicrobial susceptibility were identified by the French Biomerieux VITEK Compact2 automatic bacterial identification susceptibility analyzer, and the drug sensitivity test was supplemented by the paper diffusion (K-B) method. Results The infectious eye disease mainly was ocular trauma, with young and middle-aged men as main group. The specimens were mainly from conjunctival sac secretions, accounting for 71.05%. The positive rate of Methicillin-resistant Staphylococcus epidermidis in 114 strains of staphylococcus epidermidis was 70.18%, Staphylococcus epidermidis resistant to a variety of antimicrobials, without tigecycline, linezolid, vancomycin, quinupritin/dalfopristin. Conclusions Staphylococcus epidermidis isolated from infectious ophthalmopathy is not sensitive to a variety of commonly used antibiotics, with multiple drug resistance. Drug resistance of Staphylococcus epidermidis is very serious, so it is necessary to pay attention to strengthen the detection of Staphylococcus epidermidis drug resistance, provide guidance for clinicians and laboratory personnel, and rational use antibiotics based on drug susceptibility results. Key words: Staphylococcus epidermidis; Resistance; Infectious eye disease