Abstract
Introduction: The purpose of the study was to identify possible correlations between the quality of life, neurological disability, and functional ability in patients with multiple sclerosis.Methods: 258 patients with multiple sclerosis were included in the cross-sectional study. They were assessed with the Expanded Disability Status Scale (EDSS), the Berg Balance Scale (BBS), the Timed 25-Foot Walk Test (T25-FW), the 9-Hole Peg Test (9HPT), the Paced Auditory Serial Addition Test (PASAT-3) and the EQ visual analogue scale (EQ-VAS). Inferential statistics were used.Results: A positive correlation between the EQ-VAS and the BBS (r = 0.43, p < 0.01 ) and the PASAT-3 (r =¸0.19, p < 0.01), and a negative correlation between the EQ-VAS and the T25FW (r = –0.42, p < 0.01) and the 9-HPT (r = –0.40, p < 0.01) were shown. A negative correlation was also observed between the EDSS and the BBS (r = –0.77, p < 0.05) as well as the EDSS and the PASAT-3 (r = –0.25, p < 0.01), and a positive correlation between the EDSS and the 9 HPT (r = 0.67, p < 0.01) and the T25-FW (r = 0.80, p < 0.01).Discussion and conclusion: Associations between the variables indicate the need for complex, personalized and rational monitoring of patients with multiple sclerosis.
Highlights
The purpose of the study was to identify possible correlations between the quality of life, neurological disability, and functional ability in patients with multiple sclerosis
They were assessed with the Expanded Disability Status Scale (EDSS), the Berg Balance Scale (BBS), the Timed 25-Foot Walk Test (T25-FW), the 9-Hole Peg Test (9HPT), the Paced Auditory Serial Addition Test (PASAT-3) and the EQ visual analogue scale (EQ-VAS)
A convenience research sample of total 258 patients with MethodsMultiple sclerosis (MS) regularly examined at the Outpatient Department of Neurology at the University Medical Centre (UMC) Maribor was included in the study
Summary
The purpose of the study was to identify possible correlations between the quality of life, neurological disability, and functional ability in patients with multiple sclerosis. Methods: 258 patients with multiple sclerosis were included in the cross-sectional study. They were assessed with the Expanded Disability Status Scale (EDSS), the Berg Balance Scale (BBS), the Timed 25-Foot Walk Test (T25-FW), the 9-Hole Peg Test (9HPT), the Paced Auditory Serial Addition Test (PASAT-3) and the EQ visual analogue scale (EQ-VAS). Since the progression of MS is difficult to quantify, we should decide which aspects of the disease progression we want to capture. For this reason, the use of sensitive clinical outcome measures that can detect small changes in the disability that reliably reflect long-term changes in sustained disease progression is required. No single outcome measure will be applicable in all settings (Cohen, et al, 2012)
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