Abstract
Objectives: We evaluated the efficacy of Zinc-carbonate hydroxyapatite nanocrystals (ZCH) mouthwash (Biorepair® Mouthwash) in controlling plaque and gingivitis comparing with chlorhexidine mouthwashes. Design: Single center double blind parallel randomized clinical trial. Setting: Qassim University, College of Dentistry clinics. Participants: 88 patients with plaque induced gingivitis. 52 patients fulfilled the study requirements. Intervention: Use of mouthwash twice a day for 60s for 2 weeks. Test group used Zinc-carbonate hydroxyapatite nanocrystals (ZCH) mouthwash (Biorepair® Mouthwash) while control group used chlorhexidine mouthwashes. Follow-up 2 weeks. Main outcome measures: Gingival index and Plaque index. Results: 52 patients (control n=26; test n=26) were randomized. One subject in each group were lost to follow up, leaving 50 patients (control n=25; test n=25) for analysis. Mean Gingival and Plaque Index score at 2nd week after the use of test and control mouthwash was statically not significant, p< 0> Conclusions: Zinc-carbonate hydroxyapatite nanocrystals (ZCH) and Chlorhexidine Mouthwash (CHX) both were effective in controlling Dental Plaque and Gingivitis. Keywords: Zn-carbonate hydroxyapatite nanocrystals, Mouthwash, Chlorhexidine, Plaque, Gingivitis.
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