Clinical evaluation of ocular biometry of dual Scheimpflug analyzer, GALILEI G6 and swept source optical coherence tomography, ANTERION

Boonsong Wanichwecharungruang,Wisakorn Wongwijitsook,Kornkamol Annopawong,Anyarak Amornpetchsathaporn,Kittipong Kongsomboon,Somporn Chantra

doi:10.1038/s41598-022-07696-1

Boonsong Wanichwecharungruang, Wisakorn Wongwijitsook + Show 4 more

Open Access

https://doi.org/10.1038/s41598-022-07696-1

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Abstract

To evaluate the performance of a new swept source optical coherence tomography optical biometer, ANTERION, in ocular biometry and intraocular lens (IOL) calculation compared with the reference standard of Dual Scheimpflug Analyzer (GALILEI, G6). A prospective comparative study was conducted in a tertiary eye center. Cataract patients were scanned with both devices in a random fashion, and parameters from the devices were analyzed in terms of mean difference and intraclass correlation coefficient (ICC). Bland–Altman plots were performed to compare agreement between the devices. Ninety-six eyes from 96 patients were enrolled for evaluation. With the exception of ACD, all parameters were significantly different, but excellent agreement was revealed for all of them. The mean difference in axial length was 0.03 mm, and ICC was 0.999. Calculated IOL power with Barrett formula revealed that 93.75% were within 1 diopter and the prediction error was 0.03 diopter. Biometry of the devices were arithmetically different. However, the mean difference of the key factors in IOL calculation were small and appeared to be negligible for the purposes of clinical application. The performance of ANTERION was comparable to that of G6 in biometric measurement and IOL calculation; however, the devices cannot be used interchangeably.

Highlights

To evaluate the performance of a new swept source optical coherence tomography optical biometer, ANTERION, in ocular biometry and intraocular lens (IOL) calculation compared with the reference standard of Dual Scheimpflug Analyzer (GALILEI, G6)
A few systems are available to determine those parameters, such as Placido disc, Scheimpflug camera and OCT, and these systems can be combined in one device, for instance, the GALILEI Dual Scheimpflug Analyzer (GSA)[1], which demonstrates good repeatability in anterior segment evaluation with high accuracy of post-operative refraction after phacoemulsification and IOL implantation (PEI)[2]
Ladi et al reported the coefficient of variation (COV) for repeatability and reproducibility of central corneal thickness (CCT) obtained by GSA of 0.43% and 0.377% r espectively[8]

Summary

Introduction

To evaluate the performance of a new swept source optical coherence tomography optical biometer, ANTERION, in ocular biometry and intraocular lens (IOL) calculation compared with the reference standard of Dual Scheimpflug Analyzer (GALILEI, G6). The optical systems can be performed in a noncontact manner, and they are more convenient than the US one They have been widely used and have become the gold standard for IOL calculation. A few systems are available to determine those parameters, such as Placido disc, Scheimpflug camera and OCT, and these systems can be combined in one device, for instance, the GALILEI Dual Scheimpflug Analyzer (GSA)[1], which demonstrates good repeatability in anterior segment evaluation with high accuracy of post-operative refraction after phacoemulsification and IOL implantation (PEI)[2]. We have used GSA version GALILEI G6 (Ziemer Ophthalmic Systems AG Port, Switzerland) as the main IOL biometer in our clinic

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