Abstract
Objective To evaluate the efficacy of vitrectomy for the treatment of proliferative diabetic retinopathy in patients with chronic renal failure. Methods Clinical data of 21 eyes of 21 cases with chronic renal failure and proliferative diabetic retinopathy were analyzed retrospectively. All cases underwent vitrectomy. Results The follow-up time was 3 months. The postoperative BCVA were improved in 20 eyes (95.24%), and decreased in 1 eye (4.76%). The average BCVA(logMAR) was 2.05±0.78 before operation and 0.68±0.66 after operation. The difference in BCVA was statistically significant between pre-operation and post-operation (t=6.103, P=0.000). During perioperative period blood pressure was elevated in 18 patients. Blood pressure was increased after establishment of the three scleral cannulas in 17 patients. The increase of blood pressure repeatedly occurred in 11 patients during operation. All patients with high blood pressure were treated with appropriate treatment. All the proliferative membrane and vitreous hemorrhage were removed, retina was reattached. The postoperative complications included temporary intraocular pressure elevation in 3 eyes, pre-retinal hemorrhage in 4 eyes, ischemic optic neueopathy in 3 eyes, endogenous fungal endophthalmitis after hemodialysis deep vein catheterization in 1 eye, and heart failure caused by respiratory tract infection in 1 eye. Conclusion Carefully conducted perioperative treatment and relatively stable systemic conditions, a well-designed minimally invasive vitrectomy can effectively treat proliferative diabetic retinopathy in patients with chronic renal failure, improving visual acuity and quality of life. Key words: Vitrectomy; Renal failure, chronic; Retinopathy, diabetic, proliferative
Published Version
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