Abstract
Objective: The objective is to assess the clinical efficacy of the inclusion of release-active medication of affinity purified antibodies to protein S100 in complex rehabilitation of infants with old acute obstructive bronchitis affected by perinatal pathology of central nervous system of hypoxic genesis.Methods: 210 infants aged from 2–36 months, who suffered events of acute obstructive bronchitis, were examined. Along with clinical methods of examination, a computer bronchophonography and assessment of heart rate variability were performed.Results: Additional inclusion of release-active medication ‘Tenoten for children’ in the complex of rehabilitation of these patients had a positive effect on autonomic balance and autonomic component of bronchial obstruction. At the same time, the short course of Tenoten (1 month) did not prevent recurrent events of bronchial obstruction.Conclusions: Probably, patients with recurrent events of acute bronchial obstruction in combination with pronounced functional disorders of vegetative state require longer courses of release-active medication which normalized the activity of the central nervous system.
Highlights
210 infants aged from 2–36 months, who suffered events of acute obstructive bronchitis, were examined
Probably, patients with recurrent events of acute bronchial obstruction in combination with pronounced functional disorders of vegetative state require longer courses of release-active medication which normalized the activity of the central nervous system
Clinical efficacy of the affinity purified antibodies to the protein S100 in the complex rehabilitation of the infants with acute obstructive bronchitis affected by perinatal pathology of central nervous system
Summary
Цель: оценка клинической эффективности включения релиз-активного препарата аффинно очищенных антител к мозгоспецифическому белку S100 в комплексную реабилитацию детей раннего возраста, перенесших острую бронхиальную обструкцию на фоне легкого перинатального поражения центральной нервной системы гипоксического генеза. Пациенты с повторными эпизодами острой бронхообструкции в совокупности с выраженными функциональными нарушениями вегетативного статуса требуют более длительных курсов релизактивного препарата, нормализующего деятельность центральной нервной системы. Для цитирования: Мизерницкий Ю.Л., Мельникова И.М., Павленко В.А., Воловенко В.Н., Кондрашова Н.М. Клиническая эффективность аффинно очищенных антител к белку S100 в комплексной реабилитации детей, перенесших острый обструктивный бронхит на фоне перинатальной патологии центральной нервной системы.
Sign-in/Register to view highlights & summary 
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
