Clinical efficacy of peribulbar injection of Troxerutin and Dexamethasone for corneal edema after cataract surgery

Abstract

Objective To investigate the clinical efficacy of Troxerutin combined with Dexamethasone for corneal edema after phacoemulsification. Methods Two hundred eyes of 198 cases of serious corneal edema after cataract phacoemulsification were randomly divided into the control group and the observation group. The patients in the observation group received peribulbar injection of Troxerutin and Dexamethasone additionally except the treatments in the control group. The fading time of corneal edema of 100 eyes in each group and the number of eyes with transparent cornea at 1, 3, 5 and 7 d after the surgery were observed and compared. Results The fading time of corneal edema in the observation group was shorter than that in the control group.On one day after the surgery, the number of eyes with transparent cornea was 100 in each group.The numbers of patients with corneal edema were 45 versus 15 (t=21.43), 66 versus 32 (t=23.13) and 82 versus 45 (t=29.53), respectively, on the 3, 5, 7th d after surgery in the control group and observation group and the differences were statistically significant (P<0.005). Conclusion Troxerutin and Dexamethasone for the recovery of corneal edema after cataract surgery is effective. Key words: Surgery, cataract; Edema corneal; Dexamethasone; Troxerutin; Peribulbar injection