Clinical efficacy of pelvic floor reconstruction with autologous tissue in treatment of pelvic organ prolapse

Abstract

One hundred and twenty nine patients with pelvic organ prolapse (stage Ⅲ to Ⅳ according to POP-Q staging) diagnosed in our hospital from January 2010 to December 2016 were enrolled, among whom 66 cases underwent vaginal hysterectomy plus vaginal anterior and posterior wall repair (TO group), 63 cases underwent vaginal hysterectomy plus pelvic floor reconstruction with autologous tissue (AT group). Clinical parameters, perioperative and postoperative complications were analyzed. There was no statistically significant difference in intraoperative blood loss, indwelling urethral catheter time, length of hospital stay, and anal exhaust time between group AT and group TO (P>0.05). The average operation time of group AT was significantly longer than that of group TO (P 0.05), while the BND at 12 months after operation in group TO was increased compared to 3 months after operation (P<0.05). There were significant differences in scores of PFIQ-7 and PISQ-12 before surgery and 12 month after surgery in both groups (P<0.05). There was no statistically significant difference between the two groups in the incidence of postoperative recurrence and pressure incontinence (P<0.05). It is suggested that the stability of pelvic floor anatomical structure after pelvic floor reconstruction with autologous tissue is better than that of the traditional surgery, especially for patients with severe pelvic organ prolapse. Key words: Uterine prolapse; Urinary incontinence, stress; Rrepair of vaginal anterior and posterior wall; Pelvic floor reconstruction surgery with autologous tissue