Clinical efficacies of Jiangzhi Decoction for lipid metabolism disorder patients with traditional Chinese medicine syndrome of phlegm and turbidity retardation

Abstract

A total of 101 lipid metabolism disorder patients with traditional Chinese medicine (TCM) syndrome of phlegm and turbidity retardation were collected and randomly divided into group A: Jiangzhi Decoction (JZF) alone (n=30), group B: atorvastatin (ATV) alone (n=39) and group C: JZF plus ATV (n=32). Lipid level, liver and kidney function, total effective rate and TCM scores were observed after a course of 2 weeks.Total effective rate: Group C was significantly superior to group B (90.62% vs. 76.92%, u=1.97, P<0.05); TCM score: Group C had a statistically superior advantage over groups A and B (C vs. A, 90.62% vs. 80.00%, u=1.98, P<0.05; C vs. B, 90.62% vs. 51.28%, u=4.11, P<0.01); TC and Improvements of total cholesterol (TC) and low-density lipoprotein-cholesterol (LDL-C): Group C demonstrated marked decreases in both TC and LDL (CTC & CLDL-C vs. group A, P<0.01; CTC & CLDL-Cvs. group B, P<0.01), no abnormal liver or kidney function occurred during the follow-up period.Thus JZF and ATV may have synergic lipid-lowering effects.And single uses of JZF and ATV have no marked differences in short term efficacy. Key words: Lipid metabolism disorders; INTEGRATED TCM WM