Clinical effects of treating 72 patients with chronic renal failure and hemodialysis by warming kidney and invigorating spleen

Abstract

Objective To observe the effect of nutritional status change on hemodialysis patients of chronic renal failure and deficiency of spleen and kidney treated bytraditional Chinese medicine（TCM） of warming kidney and invigorating spleen. Methods In our center, 146 patients who were diagnosed chronic renal failure belonging to deficiency of spleen and kidney in TCM were received hemodialysis between Jun2012 and May2013. All patients were randomly divided into a treatment group （n=72） and a control group （n=74）. 74 patients in the control groupreceived conventional hemodialysis and medicine treatment, and 72 patients in treatment group received conventional hemodialysis、medicine treatment and TCM treatment of warming kidney and invigorating spleen. The comprehensive nutritional assessment of all patients were treated by modified SGAN method （MQSGAN）, anthropometric, biochemical and laboratory examination before and 6 monthsafter the treatment. Results The treatment group patients of modified SGAN（9.58±3.15）, BMI （body mass index 19.34±0.52） Kg/m2, MAC（upper arm circumference 27.51±1.95）cm, TSF（tricepsskinfold thickness 12.92± 2.42） mm and MAMC（upper arm muscle circumference 23.64±1.96）cm were significantly improved compared with the control g roup（respectively data 13.23±3.14, 17.29±0.76） Kg/m2, （24.01±2.55, 10.58±2.71） mm, （20.71±2.04）cm, P<0.05,and treatment group patients with ALB（serum albumin 38.19±1.95）g/L, PA（prealbumin 2.23±0.16）g/L, TF（transferrin 0.21±0.04）g/L, CH（cholesterol 4.02±0.26）mmol/L, BUN（blood urea nitrogen 19.58±2.17）mmol/L and SCr （creatinine 869.54±79.15）mmol/L were significant improved also compared with the control group（respectively data 33.73±1.31）g/L, （1.67±0.25）g/L, （0.17±0.02）g/L, （3.22± 0.46）mmol/L, （16.27±1.12）mmol/L, （792.73±71.65）mmol/L, P<0.05. Conclusion Traditional Chinese medicine of warming kidney and invigorating spleen can improve the nutritional status and quality of life on patients with chronic renal failure belonging to deficiency of spleen and kidney type during＆amp;nbsp;hemodialysis. Key words: Chronic renal failure; Hemodialysis; Malnutrition; Deficiency spleen and kidney; Warming kidney and invigorating spleen