Abstract
Objective To observe clinical therapeutic effects of hyperbaric oxygen (HBO) on acute cerebral infarction (ACI) complicated with carotid atherosclerosis (CAS). Methods One hundred patients with ACI complicated with CAS who were admitted for treatment in the hospital from February 2015 to February 2017 were chosen as research subjects. The patients were divided into the HBO group and the control group in accordance with different treatment methods, and at the same time, 50 healthy subjects were recruited as the normal healthy group. The control group was given routine treatment, while the HBO group received HBO in addition to routine treatment. Therapeutic effects were compared between the 2 groups, before and after treatment. Then, scores of European stroke scale (ESS), Barthel index (BI) and homocysteine (Hcy) before and after treatment were evaluated and compared between the 3 groups. Results After 3 treatment courses, the therapeutic efficacy of the HBO group (88.0%) was obviously higher than that of the control group (70.0%), with statistical significance (P 0.05). After treatment, the plasma Hcy levels of the effective group was obviously lower than that of the non-effective group (P< 0.05). Conclusions HBO treatment could obviously improve the clinical effects on acute cerebral infarction complicated with carotid atherosclerosis. Plasma Hcy level showed high clinical value in HBO treatment of ACI complicated with CAS, and it might also provide new ideas for clinical diagnosis and treatment of the disorder. Key words: Homocysteine; Hyperbaric oxygen; Acute cerebral infarction; Carotid atherosclerosis
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