Abstract

Objective: With the fast development of economy and culture, medical professionals parents are paying more and more attention to nocturnal enuresis (NE) since it rais ed the negative impact on children's health and imposes a long -term burden on families. The present clinical investigation aims to evaluate the clinical effect of pressing needle on nocturnal enuresis in children through a randomized controlled clinical trial. Materials and Methods: A total of 120 children with nocturnal enuresis were randomly assigned into pressing needle group, desmopressin group and pills Capsule group, 40 cases in each group. The children in pressing needle group were treated with pressing needles, and those in the desmopressin group and Suoquan pills were orally administrated with desmopressin and Suoquan pills, respectively. Combined behavioral therapy was also given in all the three groups during the treatment. Enuresis frequency, degree of arousal, functional bladder capacity (FBC) and postvoid residual urine volume (PRUV) were employed as the indicators to evaluate the clinical efficacy in the three groups. After 6 months of follow-up, the recurrence rate of the three groups was also analyzed for efficacy assessment. Results: The total responsive rate in pressing needle group was 95.0%, which was higher than 87.5% of Suoquan pills group (p < 0.05), and significantly higher than 77.5% of desmopressin group (p < 0.01). The frequency of enuresis was significantly lowered after treatment (p < 0.01), concurrently with an evident improvement in arousal levels in all of the three groups (p < 0.01), and the inter-group difference in post-treatment enuresis frequency and arousal level between pressing needle group and the other two groups was also statistically significant (p < 0.05). The recurrence rate of pressing needle group, desmopressin group and Suoquan pills group was 7.89%, 48.39% and 22.86%, respectively, with a difference which was statistically significant between pressing needle group and desmopressin group (p < 0.01), but not between pressing needle group and Suoquan pills group (p > 0.05). Conclusion: Pressing needle treatment showed a substantial clinical effect on enuresis in children by improving the bladder function, increasing the FBC and reducing PRUV of the bladder, as well as by enhancing the degree of arousal and lowering the recurrence rate, therefore is suggested to be considered as an option for enuresis treatment for children.

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