Abstract
Objective To investigate the relation between early postoperative intraperitoneal chemotherapy (EPIC) and the postoperative complications after curative resection, and its effect on patient＇s prognosis of gastric cancer. Methods The prognosis and postoperative complications of 174 cases with gastric cancer undergone curative resection were analyzed. Of 174 cases, 85 belonged to EPIC group, the remaining 89 cases simple operation group. Results The 5-year survival rate of EPIC group was significantly higher than that of simple operation group. The parameters of blood system between these two groups had no significant difference (P＞0.05) . The times of anal discharging gas and beginning taking food of EPIC group were significantly longer than those of simple operation group (P＜0.05) . The occurrence of complications was 11.8% (10/85) in EPIC group and 9.0(8/89) in simple operation group (P＞0.05). Among 85 cases of EPIC group, the 5- year survival rate and the occurrence of complication were not different between the general intraperitoneal chemotherapy group (53 cases) and the peritoneal hvperthermic chemotherapy group(32 cases) (P＞0.05). The times of anal discharging gas and beginning taking food were longer and the counting of WBC was lower in the peritoneal hyperthermic chemotherapy group (P＜0.05) . Conclusion EPIC can improve the prognosis of gastric cancer and does not influence the occurrence of postoperative complications.
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