Clinical characteristics and pregnancy outcomes in parturients with pulmonary hypertension: experience with 39 consecutive cases from China

Abstract

Purpose: The authors aimed to understand the clinical characteristics of pulmonary hypertension (PH) with pregnancy and pregnancy outcomes in Chinese population. Materials and Methods: The authors retrospectively analyzed 39 parturients with PH. The patients were divided into mild PH group (n = 20) and severe PH group (n = 19). They compared some clinical characteristics, as well as maternal and fetal outcomes between the mild and severe PH groups. Results: The diagnostic rate of PH before pregnancy was 7.7% and the overall maternal mortality was 15.4%. There was no significant difference in age, body mass index, average termination of gestation weeks, and New York Heart Association functional class pre-pregnancy between the mild and severe PH groups. The mortality in the severe PH group (31.6%) was significantly higher than that in the mild PH group (0%) (p p Conclusion: The overall mortality of parturients with PH is high and severe PH increase the risk of death, occurrence rate of PPH, and natality of LBWN.