Abstract
Background: This study was to collect clinical features and computed tomography (CT) findings of Influenza-Like Illness (ILI) cases, and to evaluate the correlation between clinical data and the abnormal chest CT in patients with the Influenza-Like Illness symptoms.Methods: Patients with the Influenza-Like Illness symptoms who attended the emergency department of The Six Medical Center of The PLA General Hospital from February 10 to April 1, 2020 were enrolled. Clinical and imaging data of the enrolled patients were collected and analyzed. The association between clinical characteristics and abnormal chest CT was also analyzed.Results: A total of 148 cases were enrolled in this study. Abnormalities on chest CT were detected in 61/148 (41.2%) patients. The most common abnormal CT features were as follows: patchy consolidation 22/61(36.1%), ground-glass opacities 21/61(34.4%), multifocal consolidations 17/61(27.9%). The advanced age and underlying diseases were significantly associated with abnormal chest CT.Conclusions: Abnormal chest CT is a common condition in Influenza-Like Illness cases. The presence of advanced age and concurrent underlying diseases is significantly associated with abnormal chest CT findings in patients with ILI symptoms. The chest CT characteristic of ILI is different from the manifestation of COVID-19 infection, which is helpful for differential diagnosis.
Highlights
Seasonal influenza is a global respiratory infectious disease [1]
Our hospital did not accept patients with COVID-19 infection [21]
Fatigue, sore throat, advanced age, and elevated C reactive protein were associated with abnormal chest computed tomography (CT) findings (Table 4)
Summary
Seasonal influenza is a global respiratory infectious disease [1]. The disease is usually self-limiting, but it can cause serious complications and even death in particular populations [3,4,5,6,7,8,9]. The number of hospitalizations associated with seasonal influenza in the United States is between 140,000 and 960,000 each year [7, 10]. The global annual number of deaths caused by respiratory complications related to seasonal influenza is between 290,000 and 640,000 [3]. This study was to collect clinical features and computed tomography (CT) findings of Influenza-Like Illness (ILI) cases, and to evaluate the correlation between clinical data and the abnormal chest CT in patients with the Influenza-Like Illness symptoms
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