Abstract
India leads the world with largest number of diabetic patients and is often referred to as the diabetes capital. Diabetic dyslipidemia in India is one of the main causes for Coronary Artery Disease (CAD) mortality of the world. Dyslipidemia are disorders of lipoprotein metabolism, including lipoprotein overproduction or deficiency. It is a preventable risk factor which is mostly observed in diabetes patients and that may precipitate the cardiovascular disorders. Our aim of the study is to determine the impact of type 2 diabetes mellitus (T2DM) on lipid profile of diabetic patients.
 The present study was planned in Department of General Medicine, All India Institute of Medical Sciences, Patna from july 2018 to December 2018.For the present study total 60 patients were selected. Out of 60 patients total 30 patients were enrolled in the group A as diabetic group and remaining 30 patients were enrolled in group B as normal patients. The biochemical parameters like Fating glucose level, Glycated haemoglobin (HbA1c), Total cholesterol, Triglycerides, High Density Lipid, and Low Density Lipid were estimated.
 As diabetes is a disease of self-management, appropriate nutrition (low calories, low carbohydrates, and low fat with high fiber diet) regular physical activity and proper medication to achieve good glycaemic control have to be followed. Patients of diabetes with obesity- weight management are a key factor. The diabetic patients had elevated serum total cholesterol, elevated triglyceride. The slightly elevated low density lipoprotein (LDL-C) and reduced levels of high density lipoprotein (HDL-C) indicating that diabetic patients were more prone to cardiovascular diseases. Diabetes has now become a global endemic in both developing and developed countries. Hence it is the need of the hour for early detection and prevention of this non-communicable disease.
 Keywords: Serum Triglyceride, Diabetes, LDL, HDL, etc.
Highlights
Diabetes is a chronic disease, which occurs when the pancreas does not produce enough insulin, or when the body cannot effectively use the insulin it produces
As diabetes is a disease of self-management, appropriate nutrition regular physical activity and proper medication to achieve good glycaemic control have to be followed
The slightly elevated low density lipoprotein (LDL-C) and reduced levels of high density lipoprotein (HDL-C) indicating that diabetic patients were more prone to cardiovascular diseases
Summary
Diabetes is a chronic disease, which occurs when the pancreas does not produce enough insulin, or when the body cannot effectively use the insulin it produces. This leads to an increased concentration of glucose in the blood (hyperglycaemia). Type 1 diabetes (earlier known as insulin-dependent or childhood-onset diabetes) is characterized by a lack of insulin production. Type 2 diabetes (earlier known as non-insulin-dependent or adult-onset diabetes) is caused by the body's ineffective use of insulin. It often results from excess body weight and physical inactivity. The rising prevalence of diabetes and other noncommunicable diseases is driven by a combination of factors - rapid urbanization, sedentary lifestyles, unhealthy diets, tobacco use, and increasing life expectancy. [1]
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