Abstract
Objective To study clinical application of sera thyroid hormone in diagnosis and therapy on cornary heart disease(CHD)heart failure, acute myocardial infarction(AMI) and pulmonary heart disease.Methods Determined the changes of serum triiodothyronine(T3), tetraiodothyronine(T4), free triiodothyronine (FT3), free tetraiodothyronine(FT4), thyroidstimulating hormone(TSH ), reverse triiodothyronine (rT3) and T3 /rT3 levels in 150 cases patients with CHD heart failure, 86 cases patients with AMI, 103 cases patients with pulmonary heart disease and 47 cases normal controls by chemiluminescent measurement. Results The serum levels of T3, T4, FT3, FT4, TSH, rT3 and T3 / rT3 in CHD heart failure, AMI pulmonary heart disease were compared with normal controls. Serum T4, FT4 and TSH levels were not different between above patients and normal controls(t=2.120, 2.214, 4.356, P＜0.05), but the serum T3, FFT3 and T3/rT3 were significantly decreased than those of normal controls(t=2.256, 4.416, 4.512, P＜0.05). The serum rT3 levels were significantly increased those of than normal controls (t=1.781, 1.813, 1.754, P＞0.05). The serum T3, FT3 and T3 /rT3 levels were significantly decreased in patient with CHD heart failure severity. But the serum rT3 levels was significantly increased. Conclusion The present study showed that change of serum T3, FT3 and T3 / rT3 levels in patients with CHD heart failure, AMI and pulmonary heart disease were inpartant marker and could reflect the severity of disease and used as diagnostic or treatment indicators. Key words: Heart failure,congestive; Myocardial infarction; Pulmonary heart disease; Thyroid hormones; Chemiluminescent measurements
Published Version
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