Abstract

Objective:To assess the clinical application of multicolor optical coherence tomography (OCT) using confocal scanning laser ophthalmoscopy (cSLO) in different retinal pathologies.Methods:This observational study was conducted at the Layton Rahmatullah Benevolent Trust (LRBT), Free Base Eye Hospital, Karachi, from April 2018 to June 2018. It includes 36 patients suffering from different retinal pathologies including diabetic retinopathy, age related macular degeneration, and vitreomacular interface disorders using multicolor optical coherence tomography as a screening tool.Results:It was found that automated eye tracking system of this new version tool enables ophthalmologists to take high-resolution cSLO reflectance images. The light scatter can be avoided with the use of confocal optics. Appearances of pigment changes and hemorrhages were some of the differences found when compared to the conventional CFP. About 20% in AMD, 37.5% with diabetes and 100% patients with vitreomacular interface disorders could have be easily missed by CFP.Conclusions:Multicolor OCT can provide information and figures far more authoritatively than the conventional CFP, which is highly affected by media opacities. To interpret Multicolor OCT ophthalmologists should be watchful with plenty of understanding.

Highlights

  • Imaging Techniques in the 21st century have opened new avenues for ophthalmologists to diagnose and detect different diseases of the human eye, the retina and manage them more efficiently

  • The Images were taken in patients who presented with Age related Macular Degeneration (AMD), Diabetic Retinopathy (DR) and vitreomacular interface disorders

  • Age-Related Macular Degeneration: Today one of the main application of Multicolour Optical Coherence Tomography (OCT) is in the context of Age-related Macular Degeneration (AMD) which has allowed ophthalmologists to identify it earlier and have it under regular observation during the period of anti-VEGF therapy

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Summary

Introduction

Imaging Techniques in the 21st century have opened new avenues for ophthalmologists to diagnose and detect different diseases of the human eye, the retina and manage them more efficiently. Digital Imaging as compared to the earlier film-based photography has transformed the modern ophthalmologic practices in Colour Fundus Photography (CFP), Fundus angiography (FA) and Optical Coherence Tomography (OCT).[1] These advances have proved to be precise records for patients with various retinal pathologies which in the form of high-grade images can be instantly transferred to the concerned clinicians to be used for prompt decisions and guidance.[2] The advantages that revolve around this modality are multiple with. The Color Fundus Photography (CFP) was one of the chief imaging modality throughout the 1800s, emerged as a successful tool to obtain pictures of the central and peripheral retina, macula and the optic disc in the 1950s. Computerized or semi-computerized analysis is made challenging and restricted with (1) the inconsistency of fundus pigmentation and illumination among different patients, (2) narrowranged resolution and contrast and (3) the utmost unfavorable media opacities.[5]

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