Abstract
Mesenchymal stem cells (MSCs) can differentiate into more than one type of specialist cells in our body. They are a potential source of progenitor cells for osteoblasts, chondroblasts, adipocytes, skeletal muscles, and cardiomyocytes. They may also differentiate into ecto- and endodermal cell lines, e.g., neural cells, glial cells, hepatocytes and karetinocytes. Mesenchymal cells represent only 0.001–0.01% of all bone marrow cells, are a crucial population of cells participating in the proliferative phase of damage regeneration, and they are present in nearly all body tissues, the largest number of them is in adipose tissue and blood. Properties of MSCs have formed foundations for a new interdisciplinary field, tissue engineering. Its extensive applications include aesthetic medicine, dermatology, orthopaedics, plastic surgery, physioaesthetics, and sports medicine. The aim of this study is to present selected properties of the mesenchymal stem cells exposed to an electric stimulus of frequency of 448 kHz using Capacitive-Resistive Electric Transfer (CRET) technology.
Highlights
The subject of interests will be mesenchymal stem cells, being poorly differentiated and having an ability for selfrenewal and proliferation into one or more types of specialised cells concerning observation of changes in their properties and proliferation following exposure to radio-frequency current
The best outcome was obtained using the electric current of radio frequency of 448 kHz, and this frequency was patented by the research and scientific centre in Barcelona
Beata Mazurek: Clinical Application of Impact Capacitive – Resistive Electric Transfer 448 kHz on Human Cells resistive electrode, without an insulating layer, that is, without the capacitor dielectric, the electric current is delivered with an ion flow resulting in an increase in the temperature in tissues according to the Joule's law
Summary
The subject of interests will be mesenchymal stem cells, being poorly differentiated and having an ability for selfrenewal and proliferation into one or more types of specialised cells concerning observation of changes in their properties and proliferation following exposure to radio-frequency current. Sources for effectively obtaining MSC cells include bone marrow, adipose tissue, umbilical blood, placenta, dental pulp, skeletal muscles and menstrual blood. The research conducted at the scientific and research centre in Spain showed that it is possible to stimulate proliferation of mesenchymal cells using radiofrequency current in a capacitive-resistive electric transfer (CRET) mode. The electrical stimulation gave very satisfactory results in a process of restoring damaged tissues. The best outcome was obtained using the electric current of radio frequency of 448 kHz, and this frequency was patented by the research and scientific centre in Barcelona.
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