Abstract
Anti-Mullerian hormone (AMH), a dimer glycoprotein secreted by sustentacular cells of testis and ovarian granulosa cells, belonging to the transforming growth factor β super-family. AMH is able to regulate follicular development and participate in follicular growth process, and it is relatively constant throughout the menstrual cycle compared with other ovarian reserve indicators. At present, AMH is widely used to evaluate ovarian reserve and to diagnose and evaluate the development and prognosis of ovarian diseases. It has been increasingly applied in the field of female assisted reproduction in recent years. With the development of detection technology, the sensitivity and accuracy of methods for detecting AMH are gradually improved. This review summarizes the research background, mechanism of action, clinical applications and detecting methods of AMH. Key words: Anti-Mullerian hormone; Ovarian function tests; Enzyme-linked immunosorbent assay; Chemiluminescent measurements; Trends
Published Version
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