Abstract

The aim of the study was to compare the clinical and anthropometric characteristics of patients with COPD, which differ in the degree of airways obstruction and belong to groups A, B, C, D in accordance with GOLD, 2011 classification. A total of 112 ambulatory COPD patients in remission made the study sample. Anthropometric data, body mass index, medical history, dyspnea by mMRC scale, and spirometry was performed for all patients. There was confirmed that outpatients with COPD is a heterogeneous group, in which the majority are those with moderate (48.22 %) and severe (30.36 %), airway obstruction. Despite the vast majority of men among outpatients, the percentage of women among patients with mild to moderate obstruction (22.58±5.31 %) was significantly higher (p=0.002) as compared with those with severe or very severe limitation of airflow (6.00±3.36 %). Patients with severe and very severe obstruction were of significantly older age (p = 0.024). At the same time, the distribution of patients according to the GOLD, 2011 classification, demonstrate that all groups did not differ on any of the anthropometric indicators, including gender and age (p > 0.050). Distribution of patients by groups with different risk for future exacerbations is not a mirror image of gradation in accordance with the degree of airway obstruction. Every second (50.00±4.43 % of cases) patient is included in group C and every tenth (10.20±4.32 %) belongs to the group D not due to degree of bronchial obstruction, but due to the number of exa­cerbations in the past year. Therefore, in future studies it is advisable to use both principles of patients’ classification.

Highlights

  • Ɇɟɬɨɸ ɞɨɫɥɿɞɠɟɧɧɹ ɛɭɥɨ ɩɨɪɿɜɧɹɧɧɹ ɤɥɿɧɿɤɨɚɧɬɪɨɩɨɦɟɬɪɢɱɧɢɯ ɯɚɪɚɤɬɟɪɢɫɬɢɤ ɯɜɨɪɢɯ ɧɚ ɏɈɁɅ, ɳɨ ɜɿɞɪɿɡɧɹɥɢɫɶ ɡɚ ɫɬɭɩɟɧɟɦ ɛɪɨɧɯɿɚɥɶɧɨʀ ɨɛɫɬɪɭɤɰɿʀ, ɬɚ ɩɚɰɿɽɧɬɿɜ, ɹɤɿ ɧɚɥɟɠɚɥɢ ɞɨ ɝɪɭɩ Ⱥ, ȼ, ɋ, D ɡɝɿɞɧɨ ɡ ɤɥɚɫɢɮɿɤɚɰɿɽɸ Global Initiative for Chronic Obstructive Lung Diseases (GOLD), 2011

  • Clinical-anthropometric characteristics of COPD outpatients belonging to the different groups

  • which differ in the degree of airways obstruction

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Summary

ɄɅȱɇȱɑɇȺ ɆȿȾɂɐɂɇȺ

Association between obesity and kidney disease: a systemic review and metaanalysis. After all those fat years: renal consequences of obesity. Marked association between obesity and glomerular hyperfiltration: a cross-sectional study in an African population. Ʉɥɢɧɢɤɨ-ɚɧɬɪɨɩɨɦɟɬɪɢɱɟɫɤɢɟ ɯɚɪɚɤɬɟɪɢɫɬɢɤɢ ɚɦɛɭɥɚɬɨɪɧɵɯ ɛɨɥɶɧɵɯ ɏɈȻɅ, ɩɪɢɧɚɞɥɟɠɚɳɢɯ ɤ ɪɚɡɧɵɦ ɝɪɭɩɩɚɦ ɢ ɨɬɥɢɱɚɸɳɢɯɫɹ ɬɹɠɟɫɬɶɸ ɨɛɫɬɪɭɤɰɢɢ ɞɵɯɚɬɟɥɶɧɵɯ ɩɭɬɟɣ. Ɐɟɥɶɸ ɢɫɫɥɟɞɨɜɚɧɢɹ ɛɵɥɨ ɫɪɚɜɧɟɧɢɟ ɤɥɢɧɢɤɨ-ɚɧɬɪɨɩɨɦɟɬɪɢɱɟɫɤɢɯ ɯɚɪɚɤɬɟɪɢɫɬɢɤ ɛɨɥɶɧɵɯ ɏɈȻɅ, ɨɬɥɢɱɚɸɳɢɯɫɹ ɩɨ ɫɬɟɩɟɧɢ ɛɪɨɧɯɢɚɥɶɧɨɣ ɨɛɫɬɪɭɤɰɢɢ ɢ ɨɬɧɨɫɹɳɢɯɫɹ ɤ ɝɪɭɩɩɚɦ Ⱥ, ȼ, ɋ, D ɩɨ ɤɥɚɫɫɢɮɢɤɚɰɢɢ GOLD, 2011. Ɇɟɫɦɨɬɪɹ ɧɚ ɩɨɞɚɜɥɹɸɳɟɟ ɛɨɥɶɲɢɧɫɬɜɨ ɦɭɠɱɢɧ ɫɪɟɞɢ ɚɦɛɭɥɚɬɨɪɧɵɯ ɛɨɥɶɧɵɯ, ɭɫɬɚɧɨɜɥɟɧɨ, ɱɬɨ ɩɪɨɰɟɧɬ ɠɟɧɳɢɧ ɞɨɫɬɨɜɟɪɧɨ (ɪ = 0,002) ɜɵɲɟ ɫɪɟɞɢ ɩɚɰɢɟɧɬɨɜ ɫ ɥɟɝɤɨɣ ɢ ɭɦɟɪɟɧɧɨɣ ɨɛɫɬɪɭɤɰɢɟɣ (22,58±5,31 %) ɩɨ ɫɪɚɜɧɟɧɢɸ ɫ ɥɢɰɚɦɢ ɫ ɬɹɠɟɥɨɣ ɢɥɢ ɨɱɟɧɶ ɬɹɠɟɥɨɣ ɫɬɟɩɟɧɶɸ ɨɝɪɚɧɢɱɟɧɢɹ ɜɨɡɞɭɲɧɨɝɨ ɩɨɬɨɤɚ ɜ ɞɵɯɚɬɟɥɶɧɵɯ ɩɭɬɹɯ (6,00±3,36 %). Ɋɚɫɩɪɟɞɟɥɟɧɢɟ ɛɨɥɶɧɵɯ ɩɨ ɝɪɭɩɩɚɦ ɪɢɫɤɚ ɛɭɞɭɳɢɯ ɨɛɨɫɬɪɟɧɢɣ ɧɟ ɹɜɥɹɟɬɫɹ ɡɟɪɤɚɥɶɧɵɦ ɨɬɪɚɠɟɧɢɟɦ ɝɪɚɞɚɰɢɢ ɜ ɫɨɨɬɜɟɬɫɬɜɢɢ ɫɨ ɫɬɟɩɟɧɶɸ ɨɛɫɬɪɭɤɰɢɢ ɞɵɯɚɬɟɥɶɧɵɯ ɩɭɬɟɣ. Ʉɚɠɞɵɣ ɜɬɨɪɨɣ (50,00±4,43 % ɫɥɭɱɚɟɜ) ɩɚɰɢɟɧɬ ɜɯɨɞɢɬ ɜ ɝɪɭɩɩɭ ɋ ɢ ɤɚɠɞɵɣ ɞɟɫɹɬɵɣ (10,20±4,32 %) ɨɬɧɨɫɢɬɫɹ ɤ ɝɪɭɩɩɟ D ɧɟ ɩɨ ɫɬɟɩɟɧɢ ɛɪɨɧɯɨɨɛɫɬɪɭɤɰɢɢ, ɚ ɩɨ ɤɨɥɢɱɟɫɬɜɭ ɨɛɨɫɬɪɟɧɢɣ ɜ ɬɟɱɟɧɢɟ ɩɪɨɲɥɨɝɨ ɝɨɞɚ. ɉɨɷɬɨɦɭ ɜ ɞɚɥɶɧɟɣɲɢɯ ɢɫɫɥɟɞɨɜɚɧɢɹɯ ɰɟɥɟɫɨɨɛɪɚɡɧɨ ɢɫɩɨɥɶɡɨɜɚɧɢɟ ɨɛɨɢɯ ɩɪɢɧɰɢɩɨɜ ɤɥɚɫɫɢɮɢɤɚɰɢɢ ɛɨɥɶɧɵɯ

Ƚɪɭɩɢ D
Findings
Using Cluster Analyses in COPD Patients with Multiple
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