Abstract

Migraine is the second most common after a tension-type headache and ranks third among all diseases that lead to a loss of performance among men and women under the age of 50 years. The aim of the work was to study the prevalence and severity of manifestations of anxiety, depression, autonomic and dissomnical disorders in patients with migraine without aura and chronic migraine. Material and methods. A total of 31 patients with diagnoses of migraine without aura (MwA) (group I, n = 20) and chronic migraine (CM) (group II, n = 11) were examined. The control group consisted of 30 healthy subjects. A clinical and neurological examination was carried out, experimental psychological methods included the Spielberger State and Trait Anxiety Inventory, Beck’s Depression Inventory, a questionnaire for determining autonomic disorders, a questionnaire for scoring the subjective characteristics of sleep. Results.Patients with MwA and CM were characterized by significantly higher rates of state (SА) and trait (TА) anxiety, depression, more expressed signs of autonomic dysfunction and sleep disorders compared to healthy subjects. Patients with CM had significantly higher rates of SА (1.62 times), TА (1.26 times), subjective signs of depressive mood (1.21 times), sleep disorders (1,36 times)compared topatients with MwA, which can be considered as a factor in the chronicity of HA. In both clinical groups, statistically significant positive correlations were found between the Beck depression indicator and the TА indicator; in patients with MwA, there is a negative correlation between the sleep quality indicator and the autonomic dysfunction index and the Beck depression indicator. Conclusions. For patients with MwA and CM were characterized significantly higher indices of SА and TА, depression, more pronounced signs of autonomic disorders and sleep disorders compared tohealthy subjects. Detected psycho-vegetative disorders are more common and more pronounced in patients with CM compared to patients with MwA. Determining the psycho-autonomicstate in this category of patients will allow us to individualize the approach to management and promptly developtreatment and rehabilitation modalities, if necessary, that will prevent the chronication of НА and help to improve the quality of life.

Highlights

  • Results.Patients with migraine without aura (MwA) and chronic migraine (CM) were characterized by significantly higher rates of state (SА) and trait (TА) anxiety, depression, more expressed signs of autonomic dysfunction and sleep disorders compared to healthy subjects

  • Patients with CM had significantly higher rates of SА (1.62 times), TА (1.26 times), subjective signs of depressive mood (1.21 times), sleep disorders (1,36 times)compared topatients with MwA, which can be considered as a factor in the chronicity of HA

  • Statistically significant positive correlations were found between the Beck depression indicator and the TА indicator; in patients with MwA, there is a negative correlation between the sleep quality indicator and the autonomic dysfunction index and the Beck depression indicator

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Summary

Introduction

Results.Patients with MwA and CM were characterized by significantly higher rates of state (SА) and trait (TА) anxiety, depression, more expressed signs of autonomic dysfunction and sleep disorders compared to healthy subjects. Показник депресії за опитувальником Бека у пацієнтів групи I склав Ме (Q1–Q3) = 7,50 (3,00–18,25), в групі II - Ме (Q1–Q3) = 9,00 (8,00–19,00) балів, що достовірно (P = 0,001) вище даних контрольної групи – Ме (Q1–Q3) = 0 (0–2,0) балів. В групі I нормальні значення мали 11 (55,0%) осіб, м'який ступінь депресії відмічено у 3 (15,0%), помірний – у 2 (10,0%), сильний – у 4 (20,0%) пацієнтів.

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