Clinical and psychological characteristics of alcohol-dependent patients in the formation of high quality therapeutic remission

Abstract

Objective. To identify clinical and psychological features that contribute to the formation of therapeutic remission in patients with alcohol dependence (PAD).Materials and methods. A comprehensive (clinical, experimental, psychological, statistical) comparative study was conducted of 79 PAD at the stage of therapeutic remission (icnluding 39 people in high-quality remission and 40 in low-quality remission) and 42 practically healthy individuals aged 27 to 55 (40.18 ± 10.2) years.Results. It was found that the condition of patients with high-quality PAD in remission differed from the condition of patients with the threat of relapse and healthy individuals with significantly fewer health complaints (p < 0.05), higher indicators of psychological functioning (p < 0.01) and a high level of activation of the nonspecific adaptive reaction of the body (NARB) (p < 0.001).It was found that the state of PAD in high remission differed from that of patients at risk of relapse and healthy individuals by a significantly lower number of health complaints (p < 0.05), higher indicators of psychological functioning (p < 0.01) and a high level of activation of nonspecific adaptive response of the body (NARB) (p < 0.001).Conclusion. The formation of qualitative and long-term therapeutic remission in PAD requires not only specific changes with a weakening of the manifestations of the disease, but also a high level of NARB, which provides energy support for the process of recovery with integration into a healthy society.