Clinical and morphological substantiation of need for application narrow-wave ultraviolet therapy for improving the quality of treatment and duration of remission in patients with psoriasis

Abstract

The goal is substantiating clinically and morphologi­cally the need for narrow-wave (311 nm) ultraviolet (UV) therapy to improve the quality of treatment and the du­ration of remission in patients with psoriasis. 
 Materials and methods. Under observation were 134 patients with common psoriasis (82 men and 52 women aged 23 to 65 years). For UV therapy, the PSOROLIGHT 100-6 photo- therapeutic apparatus (medical equipment Viola Ukraine, Poltava) with a wavelength of 311 nm was used. Initial radiation doses were determined depending on the skin photo type. The standard course of treatment consisted of 15-20 procedures with a regimen 3-4 times a week. 
 Results. In patients of group I, 2 times faster regression of the rash was observed, and in 54 (81.8%) patients of group I, the rash disappeared after 15-20 procedures, in 52 (78.8%) after 6-8 months, the skin process was stable , after a year in 41 (62.12%). In biopsy samples in 8 (88.9%) patients of group I, moderate acanthosis and hyperkeratosis were observed, there were no signs of parakeratosis in 7 (77.8%), the thickness of the horny layer was restored in 8 (88.9%) and granular layers of patients of the first group. 
 Conclusions. All of the above gives reason to justify the need for narrow-wave ultravio­let therapy in patients with psoriasis to improve the qual­ity of treatment and the duration of remission in patients with psoriasis. Conclusions. All of the above gives reason to justify the need for narrow-wave ultraviolet therapy in patients with psoriasis to improve the quality of treatment and the duration of remission in patients with psoriasis.