Abstract
Dysgerminoma is best known as the ovarian counterpart of seminoma of the testis Relatively uncommon tumors, dysgerminomas account for less than 2% of all ovarian cancer. We report a case of a 14 years old girl with a large and rapidly growing unilaleral ovarian dysgerminoma. Examination of the surgical specimen showed a tumor of 27x17x8 cm in size and 4800 gr. in weight. It was oval in shape with a slightly glistening fibrous capsule, soft but solid and hemorrhagic. The mass arose from the right ovary and did not invade any surrounding structures. The tumor and the ovary were torqued with its fallopian tube. Microscopic examination showed typical characteristics of ovarian dysgerminoma, with a micrometastasis in the omentum (in the vicinity of the tumor). The patient underwent a right salpingo-oophorectomy, had an uncomplicated postoperative course and received radio and chemotherapy Thirty months after the operation, the patient is in good health and with normal ultrasound and laboratory results. We believe that conservative surgery followed by adjuvant radiotherapy and chemotherapy seems to be ideal treatment in case of pure ovarian dysgerminoma when careful surgical staging confirmed the unilaterality of disease.
Highlights
Dysgerminoma is the ovarian counterpart of testicular seminoma and is composed of primordial germ cells [1,3,4]
Survival of patients with pure dysgerminoma was not affected by tumor size [3]
Dysgerminoma is the ovarian counterpart of testicular seminoma and is composed of primordial germ cells [1,3,4]. it accounts for less than 2% of all ovarian cancer [7] dysgerminoma is responsible for 10% for these cancers in woman younger than 20 years of age [5]
Summary
Dysgerminoma is the ovarian counterpart of testicular seminoma and is composed of primordial germ cells [1,3,4]. It accounts for less than 2% of all ovarian cancer [7] dysgerminoma is responsible for 10% for these cancers in woman younger than 20 years of age [5]. Most patients are between 20 and 30 years of age. Some occur in patients with gonadal dysgenesis, including pseudo-hermaphroditism. Most of these tumors have no endocrine function. But the degree of histologic atypia is variable and only one third of them is aggressive
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