Abstract
The results of clinical dental and immunological examination of 155 patients of young age (from 19 to 25 years) with chronic gastroduodenitis are presented in the work. Depending on the duration of the underlying disease, a high prevalence of inflammatory periodontal diseases, recurrent aphthous stomatitis, recurrent herpes, dry form of exfoliative cheilitis, candidiasis and an imbalance in the content of pro- and anti-inflammatory cytokines in the oral fluid in these patients. The relationship between the levels of soluble forms of intercellular adhesion molecules (sICAM-1) and pro-inflammatory cytokines, which serves as a marker of the activity of inflammatory processes in the oral cavity and gastroduodenal zone, is determined. It is established that the state of local immunity of the oral cavity depends on the degree of inflammatory processes in the oral cavity and the gastroduodenal zone.
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