Clinical and epidemiological features of pyo-inflammatory diseases in the newborns

Abstract

Aim. To study the clinical and epidemiologic features of pyo-inflammatory diseases in the newborns. Methods. Examined were 60 newborn infants who were admitted to hospital for treatment of pyo-inflammatory diseases in the department of pathology of the newborns of the Republican Clinical Infectious Diseases Hospital. In order to determine the etiology of the disease a bacteriological culture analysis from a variety of epitopes - skin, eyes, navel, nose, throat, intestine was conducted in all children. Results. The vast majority (76.7%) of the infants were born full term and as a result of natural childbirth. The most frequently reported were the infections of the skin and mucous membranes - vesiculo-pustulosis (40%), purulent conjunctivitis (20%) and omphalitis (15%), less frequently - pneumonia (6.7%), pyoderma (5%), felon (5 %) and urinary tract infections (8.3%). In 81.7% of cases the pyo-inflammatory diseases had a moderately severe course. Inflammatory changes in the blood were found only in 26.7% of cases, they manifested by leukocytosis and neutrophilia with varying degrees of severity. The vast majority (81.6%) of cases the disease developed in the first 3 days after birth, indicating either an intranatal or intrauterine mechanism of infection of these newborns. In 42.5% cases the women experienced infectious diseases of the urogenital tract during pregnancy. During microbiological investigation of the external epitopes S. aureus and S. epidermidis were the most frequently seeded strains. Conclusion. The most common pyo-inflammatory diseases in newborn infants, who are hospitalized in an infectious diseases hospital, were diseases of the skin and mucous membranes - vesiculo-pustulosis, purulent conjunctivitis and purulent omphalitis, the development of which occurred in the first 3 days after birth, and the main etiological factors of their emergence were S. aureus and S. epidermidis.