Clinical and biochemical parameters of the effectiveness a periodontal probiotic complex

Abstract

Relevance. The article describes the use of probiotics in dentistry. This is a possible alternative to antibiotic therapy for major periodontal diseases. The efficacy of the probiotic complex «ASEPTA PARODONTAL®» containing Lactobacillus plantarum, Lactobacillus brevis, vitamin D was studied in the gingivitis treatment. Purpose. To prove use of the probiotic complex in patients with gingivitis. Materials and methods . An open comparative study of the use the probiotic complex «ASEPTA PARODONTAL®» for a month was conducted, in which 37 volunteers took part, with an average age of 21.3 ± 1.0 years. Results. After a month of using the medicine, a decrease in the hygiene index by 38,19 % and the inflammation index PMA by 46,65% were revealed. The decrease of index SBI was 63,47 %, the decrease the level of halitosis on the VAS scale was 66,23%. The biochemical indicators of saliva revealed a decrease in GOT from 22,25 ± 4,06 U/l to 7,36 ± 1,24 U/l, GPT from 14,26 ± 2,61 to 4,67 ± 1,08 U/l, saliva protein level by 70,28% to 0,63 ± 0.10 g/l, a decrease in the integral index of total antioxidant activity from 1,15 ± 0,04 to 0,81 ± 0,05 mmol/l. Conclusion. The probiotic complex «ASEPTA PARODONTAL®» has anti-inflammatory effect and reduces the level of halitosis. The studied complex normalizes the biochemical parameters of saliva, characterizing the change in the microbiota of the oral cavity.