Clinical and anamnestic features of acetonemic syndrome in children with pathology of the digestive system

Abstract

Objective – to analyze clinical-anamnestic indices of acetonemic syndrome severity in children against the background of gastroenterological pathology exacerbation.Material and methods. 38 children aged from 2 to 15 with acetonemic syndrome were under doctor’s care in the Gastroenterological Department of the Regional Clinical Children Hospital in the city of Chernivtsi. Two clinical groups of observations were formed: І group included 25 children with moderate ketosis (ketonuria ++), ІІ group - 13 children with severe ketosis (ketonuria ++++). Severity of ketosis on admission was evaluated by means of semi-quantitative method to determine acetone level in urine – from one (+) to four pluses (++++) applying indicator test papers.Results. Patients with less pronounced signs of acetonemic syndrome were characterized by higher occurrence of acetonemia per year, longer period of breastfeeding, more frequently compromised individual allergic anamnesis. Patients with severe acetonemic syndrome differed by higher infectious index, a tendency to higher body mass indices, association with exacerbated gastroduodenal pathology.Conclusions. Therefore, a number of clinical-anamnestic findings, in particular, gastroduodenal pathology, higher infectious index, early transition to formula feeding, high body mass indices available, are substantial risk factors provoking more pronounced and severe acetonemic syndrome in children with digestive pathology.