Clinical analysis on the relationship of orthostatic hypotension in elderly hypertensive patients with left ventricular structure and function

Abstract

Objectives To explore the relationship of orthostatic hypotension in elderly hypertensive patients with left ventricular structure and function. Methods 101 cases of elderly patients with hypertension were selected from July 2013 to June 2015.After blood pressure measurement in vertical and decubitus position, all patients were divided into non-orthostatic hypotension and orthostatic hypotension groups, received the echocardiography and the accurate calculation of left ventricular mass index. Results Compared with non-orthostatic hypotension, orthostatic hypotension in patients with left ventricular diastolic diameter, left ventricular posterior wall thinckness and interventricular septum thickness.Left ventricular mass index significantly increased(48.13±5.54)mm vs.(52.45±1.48)mm in left ventricular diastolic diameter, (10.08±1.87)mm vs.(11.29±1.98)mm in left ventricular posterior wall thickness, (10.18±1.88)mm vs.(11.61±1.66)mm in interventricular septum thickness, and(114.59±22.72)g/m2 vs.(131.98±23.43)g/m2 〔t=4.386、2.985、4.397、8.672, in left ventricular mass index(BMI), all P<0.05〕. Left heart ventricular ejection fraction and mitral peak early/late diastolic blood flow decreased〔(60.81±4.73)vs.(53.60±2.58)and(0.93±0.23)vs(0.76±0.26)t=4.298、3.654, all P<0.05〕. Conclusions There is relationship of orthostatic hypotension with left ventricular structure and function in elderly hypertension patients, and it is essential not only to control blood pressure effectively, but also to focus on controlling orthostatic hypotension. Key words: Elderly hypertension; Orthostatic hypotension; Left ventricular structure