Clinical Analysis of Qinglongdingchuan Decoction on Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Abstract

Objective To explore the clinical effect of QinglongDingchuan Decoction on patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and analyze its mechanism. Methods From June 2017 to June 2019, patients with AECOPD were randomly divided into the observation group and the control group according to the time sequence of treatment, 40 cases in each group were observed. Control group: conventional western medicine treatment (controlled oxygen therapy, antibiotics, expectorants, bronchodilators, etc.), observation group: QinglongDingchuan decoction. 6 days is a course of observation. The routine pulmonary function, blood gas analysis, serum inflammatory factors, clinical symptoms and signs were observed. Results The observation group was superior to the control group in clinical control rate and effective rate (P < 0.05), suggesting that the treatment group was superior to the control group in overall effective rate. There were differences in symptoms, physical signs and total symptom scores between the two groups before and after treatment. The improvement of serum inflammatory factors in the treatment group was better than that in the control group. The improvement of PaC02 and Pa02 in the treatment group was better than that in the control group. Conclusion QinglongDingchuan decoction can better improve the clinical symptoms, physical signs, blood gas analysis indicators, improve the overall efficiency, and has a better effect on patients with fever AECOPD.