Clinical analysis of off-pump coronary artery bypass grafting in elderly patients with diabetes mellitus

Abstract

Objective To conduct a clinical analysis of off-pump coronary artery bypass grafting(CABG)in elderly patients with diabetes mellitus. Methods Clinical data of 115 elderly patients with or without diabetes mellitus undergone off-pump CABG from January 2012 to June 2018 were retrospectively analyzed.The impact of diabetes mellitus on the prognosis in elderly patients undergone off-pump CABG was analyzed. Results Compared with elderly non-diabetic patients, the incidences of pulmonary infection, perioperative myocardial infarction, neurological complications, psychiatric symptoms, low cardiac output syndrome, rethoracotomy, respiratory failure, arrhythmia, postoperative 30-day mortality, blood transfusion volume, mechanical ventilation time, postoperative 24-hour drainage volume, the length of hospital stay and large doses of dopamine usage(>10 μg·kg-1·min-1)increased lightly in elderly diabetic patients after off-pump CABG, but the difference had no statistical significance(all P>0.05). The incidences of postoperative renal insufficiency and incision complications were higher in elderly diabetic patients than in elderly non-diabetic patients(χ2=3.736、1.237, P=0.021、0.037). Conclusions Off-pump CABG is safe and effective for elderly diabetic patients if their blood glucose levels are controlled reasonably well. Key words: Coronary disease; Diabetes mellitus; Coronary artery bypass, off-pump