Clinical analysis of food serum specific IgE in children with allergic rhinitis in Tianjin

Abstract

Objective: To define the common food allergens in children with allergic rhinitis in Tianjin with detection of serum specific immunoglobulin E(IgE) against foods and inhalation.Method:Mediwiss(Screen Allergy) was used to determine serum specific IgE. The relationships between food allergy and gender, age, season were also analyzed.Result:Most common food allergens in children with AR in Tianjin are milk(17.28%), followed by egg white(13.79%), crab(9.56%) and cashew nuts(8.64%). Children in food-related allergy group were significantly less than that in the inhalation-related allergy group, the difference was statistically significant（P <0.05）. Among food-related allergy group, one hundred and ninty four cases are both sensitive to food allergens and inhalation allergens, and the other 34 cases are only sensitive to food allergens. There were significant differences about the positive rate of allergy between different age groups(P <0.01).There was no significant difference in the total food allergens sensitivity rate between different gender and seasonal groups（P >0.05）. The cashew and beef allergen sensitivity rates are different between male and female. The sensitivity rates of amaranth, egg, white milk, and crab are different among different age groups. The difference was statistically significant（P <0.05）.Conclusion: Milk, egg, crab, cashew nuts are the most common food allergens in children with AR in Tianjin area. Only food-related allergy is rare, food allergies are usually accompanied by inhalation-related allergy. Cashew allergen sensitivity rate was higher in male than female. Milk allergen sensitivity rate was higher in female than male. Sensitivity rate of amaranth allergen increased significantly, while that of egg milk and crab allergen decreased significantly with age.