Clinical analysis of early application of bi-level positive airway pressure ventilation in the treatment of COPD with type II respiratory failure

Abstract

Abstract: Objective: To analyze the clinical efficacy of early application of bi-level positive airway pressure ventilation in the treatment of COPD with type II respiratory failure. Method: A total of 58 patients with COPD and type II respiratory failure admitted to our hospital from January 2017 to January 2019 were randomly divided into observation group and control group, with 29 cases in each group. Among them, the control group was received routine treatment while the observation group was treated with bi-level positive pressure airway ventilation in addition of conventional treatment. The arterial blood gas analysis, mortality rate and hospitalization time of these two groups before and after treatment were compared. Result: The blood pH, partial pressure of oxygen (PaO2) and arterial oxygen saturation (SaO2) of these two groups were significantly higher after the treatment while PaO2 alone was decreased. The difference was statistically significant (P < 0.05). The results of arterial blood gas analysis in the observation group were significantly improved compared with those before treatment. The mortality rate and hospitalization time were significantly less than the control group, and the difference was statistically significant (P < 0.05). Conclusion: Early clinical application of bi-level positive airway pressure ventilation in the treatment of COPD with type II respiratory failure has a significant clinical effect in reducing the mortality rate and hospitalization time of patients, and thus it is worthy of clinical application.