Clinical analysis of 17 cases of sarcomatoid carcinoma of head and neck

Abstract

Objective:The aim of this study is to investigate the pathological features, treatment and prognosis of sarcomatoid carcinoma of head and neck. Methods:The clinical data of 17 patients with sarcomatoid carcinoma of the head and neck treated in the First Affiliated Hospital of Zhengzhou University from September 2013 to September 2020 were retrospectively analyzed, and the pathological characteristics, treatment and follow-up were summarized. Kaplan-Meier method was used to calculate the overall survival rate. Results:The histopathological examination of all patients showed the coexistence of cancer components and sarcoma components, and there was a transitional transition area between them. In terms of treatment, 12 of the 17 patients received surgical treatment, and 5 patients received palliative treatment because they could not tolerate surgery or distant metastasis; The cumulative 1-year, 3-year and 5-year survival rates of 17 patients with head and neck sarcomatoid carcinoma calculated by Kaplan-Meier method were 64.7%, 26.5%, and 13.2%, respectively. Conclusion:Pathological examination of head and neck sarcomatoid carcinoma is the gold standard for diagnosis. Radical surgery is the first choice for treatment. It has a high degree of malignancy and poor prognosis. Early diagnosis and radical surgery can improve the survival rate of patients to a certain extent.