Abstract

下咽癌位置隐蔽,早期症状不典型,患者就诊时常为癌症晚期,本病总体预后差、治疗后生活质量不佳。20世纪60年代至80年代,随着综合治疗的开展,下咽癌治疗的总体五年生存率得到了明显的提高,这使得对患者治疗后生活质量的重视程度日益增长。喉功能的保留是提高下咽癌患者生活质量的关键,因而目前临床治疗和研究的重心是在延长患者生存时间的基础上,通过多学科诊疗手段的结合提高喉功能的保留率。本文回顾下咽癌治疗的发展进程,从非手术及手术治疗两方面分别讨论晚期下咽癌(Ⅲ~Ⅳ期)喉功能保留治疗的研究进展。.

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