Abstract
A new clerodane diterpene, 15-hydroxy-16-acetoxy-ent-clerod-3-en-18-oic acid (1), together with three known clerodane diterpenes (2-4) and three known flavones (5-7), were isolated from the aerial parts of Baccharis gaudichaudiana. Their structures were elucidated on the basis of spectroscopic analysis. Compounds 2, 3, and 5 showed enhancing activity of nerve growth factor (NGF)-induced neurite outgrowth in PC 12D cells.
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