Abstract
Brain tumours are one of the most challenging medical conditions to diagnose and treat. Accurate and timely classification of brain tumours is critical for effective treatment planning and patient management. Machine learning algorithms have shown great promise in improving the accuracy of brain tumour classification. This study implemented high-grade glioma (HGG) and low-grade glioma (LGG) classification on four different 3D-MRI (magnetic resonance imaging) scans (FLAIR, T1, T1c, T2). By using four different scans, 15 different combinations were created for classification process. 3D Discrete Wavelet Transform was used to transform tumour images for feature extraction stage. 36 different wavelet types were used for image transformation. First Order Statistics (mean, variance, kurtosis, skewness, entropy, energy) were extracted from transformed images of 36 wavelet types. Support Vector Machines (SVM) algorithm classified the FOS features that were obtained on BraTS 2017 dataset. The 2-fold, 5-fold, and 10-fold cross-validations are implemented and six metrics (sensitivity, specificity, accuracy, precision, F1-score, AUC) evaluated the performance of proposed method. Consequently, proposed method achieved remarkable scores of 95.23% (sensitivity), 78.81% (specificity), 90.89% (accuracy), 92.59% (precision), 93.89% (F1-score), and 87.02% (AUC) for HGG/LGG classification of 3D brain MRI data on T1+T1c+T2 combination by 2-fold cross validation.
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