Abstract

This study was aimed at studying the pulmonary nodule (PN) classification and diagnosis through computed tomography (CT) images based on segmentation algorithms. 120 PN patients were taken as research subjects. Linear filter fine segmentation algorithm under 3D region growth was compared with the initial segmentation algorithm and applied to images of PN patients. The results showed that the segmentation effect of the proposed algorithm was at the upper-middle level. The cases of patients with smoking history were greatly more than those without (χ2 = 1.256, P < 0.05 ). Benign and malignant PNs were classified, and morphological features included rough ones and round-like ones. The size characteristics included edge length and area. The gray-scale features included the uniformity of the gray-scale value and the mean value of the gray-scale value. The operation time of pulmonary lobectomy (76.2 ± 23.1 min) was obviously longer than that of pulmonary wedge resection (27.5.2 ± 4.5 min) ( P < 0.05 ). The surgical blood loss of patients who underwent pulmonary lobectomy (125 ± 42 mL) was remarkably higher versus patients who underwent pulmonary wedge resection (51.6 ± 13.8 mL) ( P < 0.05 ). After the operation, the length of stay of patients who underwent lobectomy (8.6 ± 1.4 days) was evidently longer than that of patients who underwent wedge resection (6.4 ± 1.2 days) ( P < 0.05 ). The classification of benign and malignant PNs can effectively obtain the shape and size characteristics of PNs. Preoperative positioning surgery based on classification can shorten the operation time, reduce the amount of bleeding during the operation, and help improve the success rate of surgical resection.

Highlights

  • Lung cancer is a kind of malignant tumor, and the mucosal epithelium of the bronchus is the main source of cancer cells [1]

  • CT Imaging Characteristics of PN Patients. e diagnosis of benign and malignant PN in clinical medicine depends on the size, shape, and degree of calcification of the nodule. e CT imaging characteristics of PN mainly included the following types. e spicule sign was around the PN, with many prominent spicule shapes, generally showing a radial shape

  • Among the 120 patients, 67 patients were diagnosed as invasive PN, and the surgical method was lobectomy. 25 patients were diagnosed as PN in situ, and the surgical method was wedge-shaped pulmonary resection. e operation time and the amount of bleeding during the operation of different kinds of operations are counted in Figure 11. e operation time of pulmonary lobectomy (76.2 ± 23.1 min) was obviously longer than that of pulmonary wedge resection (27.5.2 ± 4.5 min) (P < 0.05). e surgical blood loss of patients underwent pulmonary lobectomy (125 ± 42 mL) was remarkably higher versus patients underwent pulmonary wedge resection (51.6 ± 13.8 mL) (P < 0.05)

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Summary

Introduction

Lung cancer is a kind of malignant tumor, and the mucosal epithelium of the bronchus is the main source of cancer cells [1]. Lung cancer has become the cancer with the highest incidence and death rate in the world [2]. Detection of lung cancer is mainly based on surgical treatment, supplemented by other treatments, which can remarkably improve the survival rate. Due to the influence of smoking and surrounding environmental factors, the incidence and mortality of lung cancer in countries with more developed industries in the world are still rising, and male patients occupy the first place in lung cancer [3]. PN is the early form of lung cancer, which is similar to round and irregular shape lesions. Whether there are burrs around the nodules is the criterion for judging whether PN is benign or malignant [4]

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