Abstract
Aspergillosis is an infection caused by a type of fungus. The illnesses is caused by aspergillosis infection and usually attack the respiratory system, but their signs and severity vary greatly. It has already been established that plant Cinnamomum zeylanicum belonging to the Lauraceae family has the potential to help controlling aspergillosis. This work is focused on the identification of the particular phytochemical responsible for inhibiting and decreasing the effect of aspergillosis. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that cinnamic acid can effectively deactivate aspergillosis.
Highlights
Aspergillosis is an infection caused by a type of fungus
Published works showed that Cinnamomum zeylanicum contains Procyanidin, A2, eugenol 3D, catechin, cinnamic acid curcumin, nicotine, quercetin, vanillin
Molecular docking was done with the help CDOCKER protocol of BIOVIA software under “receptorligand interaction” [4]
Summary
Aspergillosis is an infection caused by a type of fungus. The illnesses caused by aspergillosis infection usually attack the respiratory system, but their signs and severity vary greatly. Aspergillosis is the name given to a wide variety of diseases caused by fungal infections from species of Aspergillus. Different medicinal plants and their phytoextracts have shown antimicrobial action [2]. These medicinal plants play a key role in human health care. Many people rely on the use of traditional medicine [3].
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