Abstract
Cilia - the prodigal organelle
Highlights
Cilia are the oldest known cellular organelle, first described in 1675 by Anthony van Leeuwenhoek in protozoa [1]
In 1997-1998 there were a handful of publications citing work on primary cilia with the main focus on olfactory receptors (Figure 1)
The year 1998 produced the classic purification of the intraflagellar transport (IFT) complexes from Cole and Rosenbaum [9], providing the molecular basis for previous discovery from Koszminski and Rosenbaum of the intraflagellar transport process [10]
Summary
Cilia are the oldest known cellular organelle, first described in 1675 by Anthony van Leeuwenhoek in protozoa [1]. Saw the publication of Nonaka and Hirokawa’s seminal paper on nodal cilia and left-right asymmetry which helped kick-start the field [8]. This led in rapid succession to links between polycystic kidney disease and cilia, starting with the link of
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