Abstract
Symplocos racemosa Roxb. belongs to a unigenric family Symplocaceae and is used as a specific remedy for uterine complaints, vaginal and menstrual disorders. Its bark is mildly astringent, antidiarrhoeal, antidysenteric, aphrodisiac, and useful in dropsy, elephantiasis, fillaria, liver and bowel complaints, eye diseases, ulcers, menorrhagia and leucorrhoea [1]. The aqueous extract of the bark of S. racemosa on oral administration significantly stimulates serum FSH levels along with the rise in serum LH level in rat [2]. Previously, we have reported phenolic glycosides [3,4] from S. racemosa. Further investigation of the n-butanol solubles resulted in the isolation of three new benzyl derivatives, locoracemosides A, B and C (1 −3). Structure elucidation was achieved by spectroscopic and chemical evidence. The isolates displayed in vitro inhibitory activity against α-chymotrypsin. Acknowledgement: The authors are grateful to Dr. Manzoor Ahmed at the Department of Botany, Post-Graduate College, Abbottabad, Pakistan.
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