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Abstract
AbstractA 42‐year‐old Caucasian man presented with spontaneous bilateral calf pain. Past history included asthma for 8 months and sinusitis for 1 month. Investigations revealed eosinophilia, raised ESR, CRP, IgE and antimyeloperoxidase antibodies. Ethmoid sinus tissue excised during otolaryngological surgery showed non‐specific mixed inflammatory infiltrate including eosinophilia. A calf muscle biopsy demonstrated vasculitis with extravascular eosinophilia. He responded promptly to treatment with prednisone which was eventually stopped after 6 months. There is no recurrence at 6‐year follow up. It is important to recognize this presentation because prompt treatment might prevent progression of localized vasculitis to more widespread and life‐threatening vasculitis.
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