Abstract
As underline in our recent report entitled “Delayed age at menarche in chronic respiratory diseases”, during the routinely checkup clinicians should obtain accurate information and screen all the predictor factors for delayed puberty in adolescents with cystic fibrosis and asthma. Several studies have suggested that inflammation influences the reproductive function in chronic respiratory disease. Age at Menarche (AAM) is an important indicator of physiological development in women and delayed AAM has been associated with chronic illnesses. The aim of this commentary was reviewed the literature, reporting relevant and recent data about factors that influence AAM in adolescents with chronic respiratory diseases. Age At Menarche (AAM) is a major Darwinian parameter influencing the reproductive fitness of our species. It has a strong genetic determinants and it is influenced by body size and composition as well as by lifestyle and environmental conditions.
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