Abstract
Two chromones and four chromone C-glycosides (1-6), including the new 1, were isolated from the whole plant of Hypericum elodeoides. The structures were characterized by comprehensive analysis of their UV, NMR, ECD and HRESIMS data. The acid hydrolysis of Compounds 1, 2, 4 and 5 demonstrated that the chromone C-glycosides can undergo the Wessely Moser rearrangement. Compound 1 exhibited moderate α-glucosidase inhibitory activity (IC50: 456.26 ± 1.17 µM). Compound 4 could moderately reverse multidrug resistance with an IC50 value of 6.21 ± 0.40 μM (RF: 3.33) in MCF-7/Dox cells.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
