Abstract
The influence of the degree of ion-exchange resin cross-linking and size on the resolution and purity of products separated by ligand-exchange liquid chromatography was studied with mannitol-sorbitol and arabitol-xylitol mixtures. The experiment was carried out with seven calcium resins. The best results (90% recovery of pure mannitol and sorbitol and 80% recovery of pure arabitol and xylitol) were obtained with an average size of 25 μ and 7% cross-linking.
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